New publication by Leyrat et al
CRTs and individually randomized trials (IRTs) are often pooled together in meta-analyses (MAs) of randomized trials. However, the potential systematic differences in intervention effect estimates between these two trial types has never been investigated. This publication presents a meta-epidemiological study comparing intervention effect estimates between CRTs and IRTs.
Leyrat C, Caille A, Eldridge S, Kerry S, Dechartres A, Giraudeau B. Intervention effect estimates in cluster randomized versus individually randomized trials: a meta-epidemiological study. International Journal of Epidemiology. 2018;0(0)