New publication by Leyrat et al

CRTs and individually randomized trials (IRTs) are often pooled together in meta-analyses (MAs) of randomized trials. However, the potential systematic differences in intervention effect estimates between these two trial types has never been investigated. This publication presents a meta-epidemiological study comparing intervention effect estimates between CRTs and IRTs.

• Leyrat C, Caille A, Eldridge S, Kerry S, Dechartres A, Giraudeau B. Intervention effect estimates in cluster randomized versus individually randomized trials: a meta-epidemiological study. International Journal of Epidemiology. 2018;0(0)